Prediabetes: A Fundamental Text

Prediabetes affects nearly 90 million U.S. adults and more than 374 million people worldwide. But what exactly is prediabetes, and how should it be treated? Individuals with prediabetes have a high risk of progressing to type 2 diabetes. Diabetes currently affects approximately 30 million adults in the U.S. and 463 million people worldwide, and type 2 diabetes represents 90-95% of the diabetes burden. Individuals with predibetes also face increased risks of developing several complications including heart disease. Intervention at the prediabetes stage can help prevent progression to type 2 diabetes, and even lead to remission of prediabetes and a return to normal blood glucose regulation (NGR). However, a deeper understanding of the pathobiology of prediabetes is critical to the discovery and delivery of programs for preventing of diabetes.

Understanding the numerous risk factors that trigger the initial escape from NGR toward prediabetes provides critical information that enables the precise and timely targeting of preventive interventions to at-risk persons.

This book is for clinicians, researchers, public health practitioners and policy makers.